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本文采用大、小鼠为实验对家,分别对大庆、胜利、渤海三种原油油气进行了急性、亚慢性及细胞微核毒性实验研究.急性吸入毒性研究表明,大庆、胜利、渤海原油油气的LC_(50)分别为49.55g/m~3、77.54g/m~3、417.5g/m~3。亚慢性实验结果表明,动物的一般状况、生化测定、病理检查等多数指标染毒组与对照组之间没有显著性差异,但神经行为测定结果有显著性差异.细胞微核实验结果为阴性.
In this paper, large and small mice were used as experimental subjects, and acute, subchronic and cellular micronucleus toxicity experiments were carried out on Daqing, Shengli and Bohai oils.Acute inhalation toxicity study showed that Daqing, Shengli, Bohai crude oil and gas LC_ (50) were 49.55g / m ~ 3, 77.54g / m ~ 3,417.5g / m ~ 3, respectively. Sub-chronic experimental results showed that there was no significant difference in the general condition, biochemical and pathological examination between the exposed group and the control group, but there was a significant difference between the results of neurobehavioral test and the negative result of the cell micronucleus test.