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目的 :探讨反流性食管炎 (Refluxesophagitis,RE)的食管酸暴露、酸反流类型 ,及酸反流在反流性食管性食管炎的发生中的作用。方法 :使用DigtrapperMKⅢ携带式食管 2 4hpH监测仪 (PCpolrrafHR瑞典产 )测定 12例正常人及反流性食管炎患者 2 8例的食管 2 4hpH值。结果 :RE组总的、卧位和立位反流时间构成比均显著高于正常组 (P <0 0 1)。RE组卧位和立位反流次数相比较差异无显著性 (P >0 0 5 )。在RE组中 ,立位、卧位酸反流时间构成比比较差异无显著性 (P >0 0 5 )。结论 :食管长时间的酸暴露 ,可能在RE的发病中起重要的作用 ,直立位反流与卧位反流在RE的发病中有同样的作用
Objective: To investigate esophageal acid exposure, acid reflux type, and acid reflux in Refluxesophagitis (RE) in the pathogenesis of reflux esophagitis. Methods: The esophageal 24 hpH values of 28 normal subjects and 28 patients with reflux esophagitis were measured by Digtrapper MKK Ⅲ portable esophagus 24 hpH monitor (PCpolrrafHR Sweden). Results: The composition ratio of RE group in supine position and standing position was significantly higher than that in normal group (P <0.01). There was no significant difference in the number of recumbent position and standing reflux in RE group (P> 0.05). In the RE group, there was no significant difference in the time of acid reflux between the standing position and the recumbent position (P> 0.05). CONCLUSIONS: Esophageal acid exposure for a long time may play an important role in the pathogenesis of RE. Upright reflux and supine reflux have the same role in the pathogenesis of RE