妊娠期急性脂肪肝(AFLP)是妊娠晚期罕见的特发致死性的严重并发症,又称妊娠特发性脂肪肝。该病发病率低,为1/13 000~1/17 000[1],但起病急骤,病情凶险,如不能早期诊断和治疗,多造成母婴死亡。初产妇、多胎妊娠、男胎和先兆子痫是其高发因素[2]。多发生在孕28~40周,平均35周左右 Acute fatty liver during pregnancy (AFLP) is a rare severe complication of idiopathic fatal pregnancy in late pregnancy, also known as pregnancy idiopathic fatty liver. The incidence of the disease is low, 1/13 000 ~ 1/17 000 [1], but the rapid onset, dangerous condition, such as failure to early diagnosis and treatment, resulting in maternal and infant deaths. Firstborn, multiple pregnancy, male fetus and preeclampsia are its high incidence [2]. Occurred more than 28 to 40 weeks of pregnancy, an average of about 35 weeks