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作者采用麻醉狗在体心脏冠状动脉直接给药法,比较了高血糖素与去甲肾上腺素、异丙肾上腺素及多巴胺(Dopamine)对心肌收缩力的作用。药液于冠状动脉左前降支的侧枝经导管注入,在心肌内缝置微型张力计以测定左心室收缩力的变化情况。结果表明,冠状动脉注入去甲肾上腺素1.5微克、异丙肾上腺素1.5微克或多巴胺50微克均能在左心室的注射局部产生正性收缩能作用,持续50～70秒;注射高血糖素200微克同样能产生相似的局部收缩能作用,但可持续4～6分钟。对利血平化的狗,高血糖素的正性收缩能作用仍可出现,并能
The author uses the anesthetic dog in the heart of the coronary artery direct administration method, comparing glucagon and norepinephrine, isoproterenol and dopamine (Dopamine) on myocardial contractility. Liquid in the left anterior descending branch of coronary artery catheterization, in the myocardial suture micro-tonic to determine changes in left ventricular contractility. The results showed that injection of 1.5 micrograms of norepinephrine, 1.5 micrograms of isoproterenol or 50 micrograms of dopamine into the coronary arteries all produced positive systolic effects locally in the left ventricle for 50 to 70 seconds; injection of 200 micrograms of glucagon Can also produce similar effects of local contraction, but can last 4 to 6 minutes. Right reserpine dogs, glucagon positive systolic effect can still occur, and can