目的采用 LD-Ara-C 联合 IFN-α诱导慢性髓细胞白血病(CML)骨髓单个核细胞(BMMNC)分化为树突状细胞(DC),探讨其治疗 CML 有效的可能机制,为临床治疗提供理论依据。方法 Ficoll 密度梯度离心法分离初诊未治 CML 患者 BMMNC,将所得细胞分别加入不同剂量 Ara- Objective To induce the differentiation of bone marrow mononuclear cells (BMMNCs) into dendritic cells (DCs) by using LD-Ara-C combined with IFN-α to explore its possible mechanism for the treatment of CML and provide a theoretical basis for clinical treatment in accordance with. Methods BMMNCs from newly diagnosed untreated CML patients were isolated by Ficoll density gradient centrifugation. The cells were treated with different doses of Ara-