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目的探讨动态血压与高血压患者靶器官损害的相关性。方法将120例进行动态血压监测的原发性高血压病患者分为两组,其中62例存在靶器官损害患者作为A组,无靶器官损害的单纯原发性高血压病患者为B组。结果两组24h平均收缩压、脉压、血压昼夜节律、夜间平均舒张压之间差异有统计学意义(P<0.01)。结论 24h平均收缩压、脉压、血压昼夜节律、夜间平均舒张压与高血压患者靶器官损害密切相关,平稳降压有利于减少靶器官损害。
Objective To investigate the correlation between ambulatory blood pressure and target organ damage in patients with hypertension. Methods A total of 120 patients with essential hypertension who underwent ambulatory blood pressure monitoring were divided into two groups. Among them, 62 patients had target organ damage as group A, and those with no target organ damage as group B. Results 24h mean systolic blood pressure, pulse pressure, circadian rhythm of blood pressure, nighttime mean diastolic pressure difference was statistically significant (P <0.01). Conclusion 24h mean systolic blood pressure, pulse pressure, circadian rhythm of blood pressure, nighttime mean diastolic pressure and target organ damage in patients with hypertension are closely related, and steady antihypertensive help to reduce target organ damage.