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本文通过对7例多发性骨髓瘤的不同免疫类型和临床的对照分析,提出了不同免疫类型的多发性骨髓瘤,其临床表现各有特点。IgG型:异常免疫球蛋白增多,易合并感染,常有骨关节疼痛。X线片上可见较广泛的溶骨性骨破坏和骨质疏松。IgA型:突出特点有皮肤紫癜,齿龈出血、便血等出血倾向,不常合并感染。轻链型:尿中检出凝溶蛋白而血清蛋白电泳正常,易合并肾功衰竭。不分泌型:血和尿中无异常免疫球蛋白成分,血清免疫球蛋白低于正常,血沉比其它型为慢。
Based on the analysis of different immunotypes and clinical controls in 7 cases of multiple myeloma, this paper presents multiple myeloma patients with different immune types and their clinical manifestations have their own characteristics. IgG type: abnormal immunoglobulin increased, easy to merge infection, often bone and joint pain. X-ray film shows a wide range of osteolytic bone destruction and osteoporosis. IgA type: salient features are skin purpura, bleeding gums, hematochezia and other bleeding tendency, not often associated with infection. Light chain: Urine detected coagulation protein and serum protein electrophoresis is normal, easy to combine renal failure. Not secretory: no abnormal blood and urine immunoglobulin, serum immunoglobulin is lower than normal, erythrocyte sedimentation rate than other types of slow.