丛集性头痛(cluster headache,CH)是一种剧烈的爆炸样原发性疼痛,位于一侧眼眶、球后和额颞部,并伴有同侧眼球结膜充血、流泪、鼻塞及Horner综合征等[1,2]。此病人群发病率为(2～6)/10000[3],年龄20～50岁,平均约30岁[4],其中男性发病率高于女性[5]。约10%的CH病人可发展为慢性 Cluster headache (CH) is a severe explosive-like primary pain located on the side of the orbit, the posterior face of the ball and the frontotemporal area, accompanied by ipsilateral conjunctival hyperemia, tearing, nasal congestion and Horner’s syndrome [1,2]. The incidence of this patient population is (2-6) / 10000 [3], aged 20 to 50 years, with an average of about 30 years of age [4], of which male incidence is higher than that of women [5]. About 10% of CH patients can develop chronic