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52例成人急性非淋巴细胞性白血病,均为初治者,用下述方案进行诱导缓解治疗,完全缓解的病例经巩固治疗后随机分二组,分别进行6个月及15个月的维持治疗,以比较其效果。定期作血液,骨髓、生化指标、骨髓细胞体外培养及白血病细胞分泌纤溶酶原激活因子的测定。诱导缓解方案:阿糖胞苷80mg/m~2/日,持续静滴1~5天;Vp16—213 80mg/m~2/日,静滴1~5天;阿霉素40mg/m~2静滴(第6天),此为一个疗程。治疗
52 cases of adult acute non-lymphocytic leukemia, are naive, with the following programs for induction of remission treatment, complete remission of the case after consolidation therapy were randomly divided into two groups were 6 months and 15 months of maintenance treatment , In order to compare its effect. Regular blood, bone marrow, biochemical markers, bone marrow cells in vitro culture and leukemia cell secretion of plasminogen activator determination. Induction of remission program: Cytarabine 80mg / m ~ 2 / day, continuous intravenous infusion of 1 to 5 days; Vp16-213 80mg / m ~ 2 / day, intravenous infusion of 1 to 5 days; doxorubicin 40mg / m ~ 2 Intravenous infusion (day 6), this is a course of treatment. treatment