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目的:评价宫颈液基细胞学(thinprep cytology test,TCT)技术在妇女病普查中的价值,探讨对细胞学异常妇女进行筛查和随访的方法。方法:对2003年4月～2007年9月在本院进行妇女病普查的982例妇女进行宫颈TCT检查,诊断应用TBS分级标准,并对细胞学检查诊断为ASC以上者行阴道镜检查及活检。结果:982例中,细胞学诊断为ASC以上者共37例(3.77%),其中ASCUS19例,LSIL14例,HSIL3例,SCC1例。对此37例患者均采用阴道镜检查及活检进行随访,检出宫颈鳞癌1例,CINⅢ2例,CINⅡ3例,CINⅠ14例,炎症17例。结论:TCT技术及TBS诊断标准能提高宫颈病变检出率,对细胞学筛查异常的妇女可采用阴道镜及病理检查进行随访,以减少重复检查的次数。
OBJECTIVE: To evaluate the value of cervical preclinical cytology test (TCT) in the screening of women’s disease and to explore the methods of screening and follow-up of women with abnormal cytology. Methods: A total of 982 women undergoing general survey of women’s diseases in our hospital from April 2003 to September 2007 underwent cervical TCT examination. The TBS grading standards were used for diagnosis. Colposcopy and biopsy were performed on those with ASC diagnosis of cytology. Results: Of the 982 cases, 37 cases (3.77%) had cytology diagnosis of ASC or more, including 19 cases of ASCUS, 14 cases of LSIL, 3 cases of HSIL and 1 case of SCC. All the 37 patients were followed up by colposcopy and biopsy. One case of squamous cell carcinoma of the cervix, two cases of CINⅢ, three cases of CINⅡ, CINⅠ14 cases and inflammation of 17 cases were detected. Conclusion: TCT and TBS diagnostic criteria can improve the detection rate of cervical lesions, cytological screening of women with abnormal colposcopy and pathological examination can be followed up to reduce the number of repeated inspections.