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目的和方法 总结了 14 5例多结节性肝癌的治疗模式。其中全身化疗 5 5例 ,肝动脉栓塞化疗 2 9例 ,一次或多次局部切除 3 3例 ,局切后并用肝动脉插管化疗 2 8例。结果 各组AFP转阴率分别为 0、3 8.1%、75 .5 %、85 .0 % ;各组 1、2、3、5年生存率分别为 18.2 %、44 .8%、5 1.5 %、5 3 .8% ;1.9%、18.5 %、2 5 .0 %、5 1.9% ;0、7.7%、2 1.9%、48.1% ;0、3 .8%、6.9%、19.2 %。结论 多结节性肝癌手术切除优于化疗 ,切除后并用肝动脉插管化疗优于单纯局切 ,栓塞化疗优于全身化疗 (P均 <0 .0 5 )。
Objective and Methods Summarized the treatment of 145 cases of multi-nodular HCC. Including 55 cases of systemic chemotherapy, hepatic arterial chemoembolization in 29 cases, one or more local excision of 33 cases, after local cutting and hepatic artery catheterization 28 cases. Results The negative rates of AFP in each group were 0, 8.11%, 75.5% and 85.0%, respectively. The 1, 2, 3, 5-year survival rates were 18.2%, 44.8% and 51.5% , 53.8%; 1.9%, 18.5%, 25.0%, 51.9%; 0,7.7%, 2 1.9%, 48.1%; 0,3 .8%, 6.9%, 19.2%. Conclusions Surgical resection of multi-nodular HCC is better than chemotherapy. After resection, hepatic arterial cannulation is better than simple chemotherapy. Embolization and chemotherapy are better than systemic chemotherapy (all P <0.05).