论文部分内容阅读
目的了解黑龙江省大庆市人民医院药物不良反应(ADR)发生的情况及一般规律。方法对本院2005年1月至2010年6月上报的303例ADR报告,按患者的年龄、性别、给药途径、药品类别、ADR累及器官或系统及临床表现等进行统计、分析。结果 303例ADR报告中涉及的药品共12类68种,其中抗微生物药引发的ADR最多,有131例(占43.2%);其次是中药注射剂52例(占17.2%);静脉给药引发的ADR例数最多,有251例(占82.8%);以皮肤及其附件损害最为常见,有144例(占44.3)。结论临床应重视和加强ADR监测和上报工作,以减少或避免ADR的发生,促进临床合理用药,保证患者用药安全。
Objective To investigate the occurrence and general rules of ADR in Daqing People’s Hospital of Heilongjiang Province. Methods A total of 303 ADR cases reported from January 2005 to June 2010 in our hospital were collected and analyzed according to their age, sex, route of administration, drug category, ADR involved organ or system and clinical manifestation. Results A total of 68 drugs were involved in the 303 ADR cases, of which 68 were ADRs caused by antimicrobial agents, accounting for 43.2% of the total. Among them, 52 cases (17.2%) were injected with traditional Chinese medicine (TCM) injection; The highest number of ADR cases, 251 cases (82.8%); the most common damage to the skin and its attachments, 144 cases (44.3). Conclusion Clinical should pay attention to and strengthen the work of ADR monitoring and reporting in order to reduce or avoid the occurrence of ADR, to promote clinical rational use of drugs and ensure the safety of patients.