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目的:观察高敏C反应蛋白(hs-CRP)在2型糖尿病(DM)及DM伴大血管病变时的浓度变化。方法:84例2型DM患者按有无大血管病变分为伴大血管病变组(A组)44例,不伴大血管病变组(B组)40例,另选30例健康者作为正常对照组(C组),均检测血清hs-CRP值及糖化血红蛋白、空腹血糖、总胆固醇、三酰甘油,高、低密度脂蛋白胆固醇。结果:A组血清hs-CRP水平明显高于B组及C组(均P<0·01),B组高于C组(P<0·01)。结论:hs-CRP对DM患者发生大血管病变的预测具有重要意义。
Objective: To observe the changes of hs-CRP in patients with type 2 diabetes (DM) and DM with macrovascular complications. Methods: Forty-four patients with type 2 DM were divided into two groups according to the presence or absence of macrovascular disease: 44 patients with macrovascular disease (group A), 40 patients without macrovascular disease (group B), and 30 healthy subjects as normal control Group C (group C), serum hs-CRP and HbAlc, fasting blood glucose, total cholesterol, triglyceride, high and low density lipoprotein cholesterol were measured. Results: The serum hs-CRP levels in group A were significantly higher than those in group B and C (all P <0.01), and in group B were higher than those in group C (P <0.01). Conclusion: hs-CRP is of great significance for the prediction of macroangiopathy in DM patients.