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目的探讨前列腺癌患者血清PSA与前列腺癌患者Gleason分级和临床分期的相关性。方法经穿刺病理检查确诊为前列腺癌患者112例。采用Spearman等级相关分析来研究穿刺前检测血清PSA与前列腺癌的病理分级、临床分期以及前列腺体积的关系。结果PSA值与前列腺癌的病理分级、临床分期及前列腺体积有相关性。结论PSA值不仅是前列腺癌的筛选指标,而且对前列腺癌进展的评估及预测有重要意义。
Objective To investigate the correlation between serum PSA level and Gleason grade and clinical stage in patients with prostate cancer. Methods Totally 112 cases of prostate cancer were diagnosed by biopsy. Spearman rank correlation analysis was used to study the relationship between serum PSA and the pathological grade, clinical stage and prostate volume before prostatectomy. Results The PSA value was correlated with the pathological grade, clinical stage and prostate volume of prostate cancer. Conclusions PSA value is not only the screening index of prostate cancer, but also has important significance for the assessment and prediction of the progress of prostate cancer.