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用葡萄糖酸锌、亚硒酸钠和维生素E,对129名Ⅰ期矽肺患者和观察对象作了治疗前后免疫球蛋白IgA、IgG和IgM的测定。结果表明:观察对象与Ⅰ期矽肺Ⅰ组,治疗前后相比免疫球蛋白IgA有显著性降低(P<0.05),观察对象Ⅰ组和Ⅱ组的免疫球蛋白IgM,治疗前后相比也有显著性降低(P<0.05),其余项目均有降低趋势,但未见显著性差异(P>0.05)。
129 patients with stage I silicosis and their observation subjects were treated with zinc gluconate, sodium selenite and vitamin E for the determination of immunoglobulin IgA, IgG and IgM before and after treatment. The results showed that the immunoglobulin IgA was significantly lower in the observation group than in the stage I silicosis group Ⅰ (P <0.05), and the immunoglobulin IgM in group Ⅰ and group Ⅱ was also significantly higher than before treatment (P <0.05). The remaining items all showed a decreasing trend, but no significant difference (P> 0.05).