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肝硬化是严重影响人类健康的疾病,目前尚缺乏有效的治疗方法,而肝纤维化是肝硬化发展过程的中心环节,因此控制肝纤维化已广泛受关注.研究结果显示,基质金属蛋白酶(MMP13)及星状细胞(HSC)在肝纤维化过程中起重要作用.本研究就MMP13及HSC在肝纤维化过程中的作用研究进展进行了综述.1肝纤维化病因肝纤维化是由实质性损伤引起的炎症所导致
Liver cirrhosis is a serious disease affecting human health, and currently there is a lack of effective treatment, and liver fibrosis is the central part of the process of liver cirrhosis.However, it has been widely concerned about the control of liver fibrosis.The results show that matrix metalloproteinase (MMP13 ) And stellate cells (HSC) plays an important role in the process of hepatic fibrosis.In this study, we reviewed the research progress of MMP13 and HSC in the process of hepatic fibrosis.1 The causes of hepatic fibrosis Liver fibrosis is caused by the substantial Damage caused by the inflammation caused