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目的：为提高脑胶质瘤放射疗效，对113例脑胶质瘤术后放疗的影响疗效的因素进行分析。方法：所有病人皆用60Co行术后放疗，剂量为39～60Gy／4～6周。结果：1、3、5年生存率高分级组分别为80．9％、30．9％、16．2％，低分级组分别为77．8％、62．2％、42．2％，两组的3、5年生存率差异有显著统计学意义（P＜0．05）。高剂量组1、3、5年生存率分别为83．3％、66．6％、39．4％，低剂量组分别为80．9％、25．5％、12．8％，两组3、5年生存率差异显著（P＜0．05）。放疗与手术间隔时间的长短、年龄40岁上下不同组的生存率的差异亦显著。结论：影响疗效的主要因素为病理类型，放疗剂量，放疗与手术间隔时间和年龄。为提高疗效，放疗剂量应达50～60Gy，放疗与手术间隔宜为2～4周，对不同年龄组和不同的病理分级宜采用不同的治疗方法。
Objective: To investigate the effect of radiotherapy on glioma after radiotherapy for 113 patients with glioma. Methods: All patients were treated with 60Co postoperative radiotherapy at a dose of 39-60 Gy/4 to 6 weeks. Results: The 1-, 3-, and 5-year survival rates were 80.9%, 30.9%, and 16.2% in the high-grade group, and 77.8%, 62.2%, and 42.2% in the low-grade group, respectively. There was a statistically significant difference in the 3-year and 5-year survival rates between the two groups (P<0.05). The 1-, 3-, and 5-year survival rates of the high-dose group were 83.3%, 66.6%, and 39.4%, respectively; the low-dose groups were 80.9%, 25.5%, and 12.8%, respectively. The difference between the 3 and 5 year survival rates was significant (P<0.05). The difference in the survival rate between radiotherapy and surgery, the age of 40 years old, and the different groups were also significant. Conclusion: The main factors influencing the curative effect are pathological type, radiotherapy dose, radiotherapy and operation interval and age. In order to improve the curative effect, the radiation dose should reach 50-60Gy, and the interval between radiotherapy and surgery should be 2 to 4 weeks. Different treatment methods should be adopted for different age groups and different pathological grades.