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病例报告:男性,62岁,因患严重的复发性溃疡5年而初诊。溃疡发生在臀部、大腿、小腿、耳和手背等温度较低的皮肤表面。发疹前几个月曾患肝炎,血清HBsAg阳性。检查发现上述部位有明显网状青斑,下肢有紫癜及色素沉着斑。病理证实为皮肤结节性动脉周围炎。血中发现冷沉球蛋白为6g/L,为混合成分的冷沉球蛋白包括IgG,IgA,IgM,C3和C4。血清总补体水平正常,未发现C3转化产物。室温下,在用EDTA—抗凝标本制成血
Case report: Male, 62 years old, first diagnosed with severe recurrent ulcer for 5 years. Ulcers occur in the buttocks, thighs, calves, ears and back of the hand and other lower temperature skin surface. A few months before the rash had hepatitis, serum HBsAg positive. Inspection revealed that the above sites have a significant reticulocyte, purpura and pigmentation spots lower extremities. Pathological confirmed as skin nodular periarteritis. The amount of cryoglobulin found in the blood was 6 g / L, and cryoglobulin, which is a mixed component, includes IgG, IgA, IgM, C3 and C4. Serum total complement levels were normal, did not find C3 conversion products. Blood is prepared at room temperature using EDTA-anticoagulant samples