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[目的]建立成都市双生子登记系统,并对双生子登记方法进行比较。[方法]从成都及周边地区募集6~16岁双生子,通过寄信及走访学校两种途径进行双生子登记。通过提取颊黏膜DNA进行双生子卵型鉴定。[结果]调查了双生子213对。其中,同性别双生子175对(男性77对,女性98对),不同性别37对。213对双生子中有卵型结果的189对(93%),其中同卵双生子99对,异卵双生子90对。213对调查者中,来源于学校途径的有159对,来源于寄信途径的有62对,其中有8对重叠。学校途径的应答率高于寄信途径(χ2=3.61,P﹤0.05)。[结论]成都双生子登记系统已取得了初步进展。为了更加快捷、高效的收集双生子,可以主要从小学进行募集,进一步壮大成都双生子登记随访系统,为日后的研究奠定基础。
[Objective] To establish a twin registration system in Chengdu and compare twins registration methods. [Method] Raise twins from 6 to 16 years old from Chengdu and the surrounding areas and register twins through two methods: sending mail and visiting school. Identification of twin eggs by extraction of buccal mucosal DNA. [Results] 213 pairs of twins were investigated. Among them, the identical twins 175 pairs (77 males, 98 females), 37 different gender. Of the 213 pairs of twins, there were 189 pairs (93%) of the oval-shaped results, of which 99 pairs of identical twins and 90 pairs of fraternal twins. Of the 213 respondents, 159 were from schools, 62 from mailing, of which 8 were overlapping. The response rate of school route was higher than that of mailing route (χ2 = 3.61, P <0.05). [Conclusion] The twins registration system in Chengdu has made some initial progress. In order to collect twins more quickly and efficiently, they can be recruited primarily from primary schools to further strengthen the twin-birth registration system in Chengdu, laying the foundation for future research.