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鱼油中的二十碳五烯酸(EPA)有抑制肿瘤生长和转移的作用,但这种物质极不稳定,不利于长期贮存。本次对二十碳五烯酸乙酯(EPA乙酯)加速试验得到的EPA衍生物(EPAD)进行研究,并探讨了它们对Lewis肺癌(LLC)细胞、成人皮肤微血管内皮细胞(HMVEC)O-2生成及DNA合成的影响。方法:①EPA乙
Eicosapentaenoic acid (EPA) in fish oil inhibits tumor growth and metastasis, but this substance is extremely unstable and not conducive to long-term storage. The present EPA derivatives (EPADs) obtained from the accelerated test of ethyl eicosapentaenoate (EPA ethyl ester) were studied and their effects on Lewis lung carcinoma (LLC) cells, adult dermal microvascular endothelial cells (HMVEC) O -2 generation and DNA synthesis. Methods: ①EPA B