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应用PCR技术检测口腔粘膜病损中HPV的感染情况,病损包括白斑、扁平苔藓、慢性盘状红斑狼疮、日光性唇炎、鳞癌及鳞癌术后上皮高度增生共34例。结果表明在口腔癌与白斑中可存在HPV的感染,HPV可能是口腔癌的致病因子之一。
Polymerase chain reaction (PCR) was used to detect the infection of HPV in oral mucosal lesions. Lesions included leukoplakia, lichen planus, chronic discoid lupus erythematosus, solar cheilitis, squamous cell carcinoma and epithelial hyperplasia of squamous cell carcinoma in 34 cases. The results show that there may be HPV infection in oral cancer and leukoplakia, HPV may be one of the causative agents of oral cancer.