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目的：探讨宫颈癌对化疗的疗效。方法：８例巨块型宫颈癌（肿瘤直径＞５ｃｍ）患者的平均年龄为２８．１岁。其中Ⅰｂ期３例，Ⅱａ期２例，Ⅱｂ期３例；鳞癌４例，腺癌３例，腺鳞癌１例。使用ＶＣＲ、ＤＤＰ、ＣＴＸ及ＶＭ２６静脉联合化疗一疗程。８例中，７例有效（有效率８７．５％），５例显效（６２．５％），其中４例鳞癌，１例腺癌。７例患者成功地进行了宫颈癌根治术，１例改为放疗。１例合并金葡菌感染抗菌素治疗无效，经化疗后得以控制。结论：年轻宫颈癌患者发病率上升，病程短发展快，以铂类为主的联合化疗对大多数宫颈癌是有效的，且鳞癌较腺鳞癌和腺癌敏感。使用铂类为主的联合化疗作为巨块型宫颈癌术前缩小肿瘤有利于手术，不失为一种好方法，尤对无放疗条件的地区和单位可达改善预后的效果。对宫颈癌合并感染抗菌素疗效差者，可在支持疗法的基础上并用化疗
Objective: To investigate the efficacy of cervical cancer on chemotherapy. Methods: The average age of 8 patients with massive cervical cancer (>5cm tumor diameter) was 28.1 years. There were 3 cases in stage Ib, 2 cases in stage IIa, 3 cases in stage IIb, 4 cases of squamous cell carcinoma, 3 cases of adenocarcinoma, and 1 case of adenosquamous carcinoma. Use VCR, DDP, CTX and VM26 intravenous chemotherapy for one course of treatment. Of the 8 cases, 7 were effective (87.5% effective) and 5 were markedly effective (62.5%), of which 4 were squamous cell carcinoma and 1 was adenocarcinoma. Seven patients successfully underwent radical surgery for cervical cancer and one patient was treated with radiotherapy. One case of antibiotics with Staphylococcus aureus infection was ineffective and could be controlled after chemotherapy. CONCLUSIONS: The incidence of cervical cancer in young patients is increasing, and the duration of the disease is shorter. Platinum-based combination chemotherapy is effective for most cervical cancers, and squamous cell carcinoma is more sensitive than adenosquamous and adenocarcinoma. The use of platinum-based combination chemotherapy as a bulk-type cervical cancer to shrink the tumor before surgery is beneficial to surgery, which is a good method, especially for areas and units without radiotherapy conditions to improve the prognosis. Patients with poor efficacy in cervical cancer co-infection of antibiotics can be combined with chemotherapy based on supportive therapy