补体系统是固有免疫系统的重要组成之一,可通过控制微生物感染、增强免疫反应和清除免疫复合物等对肾脏起到保护作用。但是补体产物的过度活化、调节异常和补体缺陷却能参与多种肾脏疾病的发生发展。本文就近年来补体与肾脏关系的研究进展进行综述。 Complement system is an important part of the innate immune system. It can protect the kidneys by controlling microbial infection, enhancing immune response and removing immune complexes. However, excessive activation of complement products, abnormal regulation and complement defects are involved in the development of a variety of kidney diseases. This review summarizes the recent progress of research on the relationship between complement and kidney.