树突状细胞 (DC)作为目前已知的功能最强的抗原提呈细胞 ,也是抗原特异性免疫应答的始动者 ,可在体内外向T细胞提呈抗原并诱发CTL反应 ,在抗肿瘤免疫中发挥重要作用。近年来采用DC疫苗进行肿瘤免疫治疗研究获得一些突破性进展。本文就DC在肿瘤免疫中的作用机制、与泌尿系肿瘤免疫逃逸的关系、DC疫苗免疫治疗原理与制备方法及其在泌尿系肿瘤治疗方面的最新研究进展作一综述 Dendritic cells (DCs) are the most potent antigen-presenting cells known to date. They are also the initiators of antigen-specific immune responses. They can present antigens to T cells in vitro and in vivo and induce CTL responses. Anti-tumor immunity In the play an important role. In recent years, DC vaccines for tumor immunotherapy research made some breakthroughs. This review summarizes the mechanism of DC in tumor immunity, its relationship with urinary tumor immune escape, the principle and preparation of DC vaccine immunotherapy and the latest research progress in the treatment of urological tumors