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大宗家族性颅内动脉瘤(FIAs)病例与同一地区散发性颅内动脉瘤之间的比较分析尚无报道。本文作者将芬兰东部85个家庭中的167例家族性颅内动脉瘤患者共计215个动脉瘤,与983例非家族性动脉瘤(non-FIAs)共计1296个动脉瘤的资料进行了对照分析。所有FIAs均通过影像学检查,尸检或死亡证明书等材料证实。动脉瘤体大小是通过血管造影片在无放大的情况下确定的;作者在分析中对结果进行了多项统计学处理。 结果:1.性别:FIA组女性稍多,男女之间在平均发病年龄上都较低。那些一家有3个以上病例的家庭中男女之比大致相等。男性3/4为大脑前动脉动脉瘤(AComAs),女性75％为大脑中动脉动脉瘤(MCAs)。在FIA组中有57对同胞兄妹,其中27对在10年内相继发病。因此,作者采用二种统计学方
There have been no reports of major familial intracranial aneurysms (FIAs) with sporadic intracranial aneurysms in the same area. The authors compared a total of 215 aneurysms in 167 patients with familial intracranial aneurysms in 85 families in eastern Finland to a total of 1,296 aneurysms in 983 non-familial aneurysms (non-FIAs). All FIAs were confirmed by imaging, autopsy or death certificates. Aortic aneurysm size was determined by angiogram without magnification; the authors performed a number of statistical analyzes of the results in the analysis. Gender: FIA group slightly more women, men and women in the average age of onset are lower. Those who have more than three cases of family, the ratio of men and women are roughly equal. Three quarters of men were AComAs and 75% of women were middle cerebral artery aneurysms (MCAs). There were 57 siblings in the FIA group, 27 of which developed in 10 years. Therefore, the author uses two statistics