[Objective]To optimize the extraction technology of quercetin in Fagopyrum tataricum (L.) Gaertn. bran. [Method]After the pretreatment of Fagopyrum tataricum (L.) Gaertn. bran,whose quercetin glycoside was enzymically degraded into quercetin,the further extraction was operated to study the effects of methanol concentration,solid-liquid ratio and extraction temperature on the extraction yields of quercetin in Fagopyrum tataricum (L.) Gaertn. bran. [Results] In the test range,with the increasing of methanol concentration,temperature and solid-liquid ratio,the quercetin extraction rate of Fagopyrum tataricum (L.) Gaertn. bran increased gradually; the sequence of factors affecting extraction rate was methanol concentration,temperature and solid-liquid ratio; the optimal combination of factors was A4B4C4 , considering many aspects as the cost,workload and efficiency,and the combination of A3B2C3 was chosen under the optimal conditions which was extraction temperature of 35 ℃ ,ratio of solid to liquid of 1∶ 25 (g/mL) ,methanol concentration of 70% ,extraction time of 1 h. [Conclusion]After further testing,the quercetin extraction rate could reach 89. 3% under the optimal conditions with good reproducibility.