Khler和Milstein于1975年首创了淋巴细胞杂交瘤技术,该杂交瘤能在体外无限制地产生纯度高,特异性强的单克隆抗体(简称McAb)。短短的十年来,人们对单克隆抗体作了大量的研究,证实了它是免疫学上最重要的技术,是生物学和临床医学研究中杰出的多用途的工具。 单竞隆抗体制备的现状 Khler and Milstein first introduced the lymphoma hybridoma technology in 1975. This hybridoma can produce highly pure and specific monoclonal antibodies (abbreviated as McAb) in vitro without restriction. In the past ten years, a great deal of research on monoclonal antibodies has been carried out, confirming that it is the most important immunological technology and an outstanding multi-purpose tool for the study of biology and clinical medicine. The current status of single-stranded antibody preparation