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目的:探讨全肺放疗治疗双肺多发转移癌的近期疗效及毒副作用;方法:回顾性分析我院收治的双肺多发转移癌患者19例,均给予全肺放疗或全肺放疗+局部小野补量,观察治疗效果;结果:放疗结束后1月评价疗效,CR15.8%,PR57.9%,有效率(CR+PR)73.7%;骨髓抑制:Ⅰ度47.3%(9/19);Ⅱ度15.7%(3/19);Ⅲ度0;Ⅳ度0。急性放射性肺炎:Ⅰ级21%(4/19);Ⅱ级10.5%(2/19);Ⅲ级5.2%(1/19);Ⅳ级0(0/19)。结论:全肺放疗+局部小野补量可用于双肺转移癌的治疗,可获得较好疗效,临床上应当进一步推广应用。
Objective: To investigate the short-term curative effect and toxic side effects of whole lung radiotherapy in the treatment of multiple lung cancer with multiple metastases. Methods: A retrospective analysis of 19 patients with multiple lung metastases in our hospital, were given whole lung radiotherapy or whole lung radiotherapy + Results: The efficacy of CR15.8%, PR57.9%, effective rate (CR + PR) 73.7%; bone marrow suppression: Ⅰ degree 47.3% (9/19); Ⅱ Degree 15.7% (3/19); Degree III; Degree 0; Acute radiation pneumonitis: Grade I 21% (4/19); Grade II 10.5% (2/19); Grade III 5.2% (1/19); Grade IV 0 (0/19). Conclusion: Whole lung radiotherapy + local dose of small amount of wild can be used for the treatment of lung metastases, get better curative effect, and should be further popularized and applied clinically.