肠球菌已成为医院感染的重要病原。从70年代首次报道肠球菌高耐庆大霉素开始,肠球菌对庆大霉素等氨基糖苷类药物的高水平耐药不断增加,如希腊在1993～1994年粪肠球菌和屎肠球菌对庆大霉素高水平耐药(HLGR)发生率2 0 %左右,1996～1997年则分别达到4 3 7%和2 6 3% ;北京四家医院 Enterococcus has become an important pathogen of nosocomial infection. From the first report of the 70’s enterococci high resistance to gentamicin began, enterococci on gentamicin and other aminoglycosides drugs such as high levels of resistance continue to increase, such as Greece in 1993 ~ 1994 Enterococcus faecalis and Enterococcus faecium pair The incidence of gentamicin high level drug resistance (HLGR) was about 20%, reaching 43.7% and 26.3% respectively from 1996 to 1997. Four hospitals in Beijing