55岁女性腔隙性脑梗死患者,既往有甲状腺机能减退3年,现口服左甲状腺素钠6.25μg,隔日1次。静脉滴注棓丙酯注射液(欣洫通)180mg/次,1次/d。在静滴棓丙酯注射液同日口服左甲状腺素钠片时,患者诉头痛、头胀,血压由原126～130/70mmHg升至150/90mmHg,口服氯沙坦钾(科素亚50mg/片)100mg后血压下降至140/80mmHg。2d后再次合用时,血压又升高到146/90mmHg。 55-year-old female patients with lacunar infarction, previous thyroid hypothyroidism for 3 years, is now taking oral levothyroxine 6.25μg, every other day. Intravenous injection of propyl gallate injection (Xin Yan Tong) 180mg / time, 1 time / d. In intravenous infusion of propyl gallate on the same day oral levothyroxine sodium tablets, the patient complained of headache, head swelling, blood pressure from the original 126 ~ 130 / 70mmHg rose to 150 / 90mmHg, oral losartan potassium ) 100mg blood pressure dropped to 140 / 80mmHg. When combined again after 2 days, the blood pressure increased to 146/90 mmHg.