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我院1983年收治2例弥漫性甲状腺肿并甲亢患者,由于用他巴唑治疗导致白细胞迅速减少,粒细胞极度缺乏。为了提高对本病的认识,特报告如下。病例报告例一,女性,20岁。因怕热、多汗、食亢、消瘦乏力,甲状腺肿大,T_31.9ng/ml,T_424μg/ml,诊为甲亢,服他巴唑6月余(其间间歇停药2月)症状减轻。入院前2天,因受凉畏寒、发热,咽痛,粒细胞减少,于1984年8月24日急诊入院。既往体差,无甲状腺疾病及过敏史。体检:T40℃,P126次/分,R25次/分,BP106/60,消瘦,急性病容,突眼不明
In our hospital in 1983 admitted 2 patients with diffuse goiter and hyperthyroidism, due to treatment with methimazole rapidly decreased white blood cells, extremely lack of granulocytes. In order to raise awareness of the disease, special report is as follows. Case report, one female, 20 years old. Due to fear of heat, sweating, eating hyperthyroidism, weight loss, goiter, T_31.9ng / ml, T_424μg / ml, diagnosed as hyperthyroidism, taking methimazole more than 6 months (during intermittent withdrawal in February) to reduce the symptoms. 2 days before admission, due to cold chills, fever, sore throat, neutropenia, in August 24, 1984 emergency admission. Previous body size, no thyroid disease and allergies. Physical examination: T40 ℃, P126 times / min, R25 beats / min, BP106 / 60, weight loss, acute illness, exophthalmos