一、概述美沙酮一直是用于治疗阿片类戒断症状的主要药物，但它自身容易形成依赖，且可流失进入黑市转化为毒品。因此，限制了其广泛应用。英国很多全科医生拒绝使用美沙酮脱毒。为解决美沙酮的问题，人们探索了用非阿片类药品进行脱毒，其中的代表药物是可乐定，它可控制... I. Overview Methadone has been the leading drug for the treatment of opiate withdrawal symptoms, but it is easily relied on and can be lost to the black market and converted to drugs. Therefore, it limits its wide application. Many general practitioners in Britain refuse to use methadone. To solve the problem of methadone, people have explored the use of non-opioid drugs for detoxification, the representative of which is clonidine, which can control ...