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钙盐有正性肌力作用,又影响血管平滑肌张力。血管平滑肌收缩需钙离子参与,所以高钙或低钙血症的外周血管变化也将影响病人的血压。一、总钙与离子钙细胞外的钙来自循环血液,也提供细胞内各项活动之用。血钙可分为结合(复合)和离子(游离)两种形态,仅离子钙具有生理活性。给狗注射葡萄糖酸钙和柠檬酸三钠后,尽管血清总钙量增高,但离子钙浓度却减少,经测定左室压力上升最高变化率
Calcium salt has a positive inotropic effect, but also affect vascular smooth muscle tension. Vascular smooth muscle contraction requires calcium ions involved, so high calcium or hypocalcemia peripheral vascular changes will also affect the patient’s blood pressure. First, the total calcium and ionized calcium Extracellular calcium from the circulating blood, but also provide various activities within the cell. Calcium can be divided into binding (complex) and ion (free) two forms, only ionized calcium has physiological activity. After injecting calcium gluconate and trisodium citrate into the dog, although the total serum calcium increased, the ionized calcium concentration decreased. The highest rate of change of the left ventricular pressure rise