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目的了解山西省太原市SARS临床确诊病例半年后的血清抗体水平、胸部和股骨头影像学的变化。方法对132例太原市2003年3月11日~7月5日临床确诊的SARS病例进行随访问卷调查、血清学抗体检测及肺部和股骨头影像学检查,并分析比较。结果SARS临床确诊病例半年后的主要症状为气短、关节肌肉痛、心悸和烦躁;女性患者各种症状的发生率均高于男性;血清抗体与心悸、烦躁和肌肉关节痛的发生情况有统计学关联;血清抗体阳性率与入院时间有关联。结论太原市SARS病例存在过度诊断现象,血清抗体阳性率随着入院时间的推移逐步下降;部分确诊病例出院后合并股骨头缺血性坏死改变。
Objective To investigate the changes of serum antibody level, thoracic and femoral head imaging in the clinically diagnosed cases of SARS in Taiyuan, Shanxi Province. Methods A total of 132 cases of SARS cases diagnosed in Taiyuan from March 11 to July 5, 2003 were investigated with follow-up questionnaires, serological antibodies and pulmonary and femoral head imaging examinations. Results The main symptoms of the clinically confirmed SARS cases were shortness of breath, joint muscle pain, heart palpitations and irritability; the incidence of various symptoms in women was higher than that in men; the incidence of serum antibody and heart palpitations, irritability and muscle joint pain were statistically significant Association; serum antibody positive rate associated with admission time. Conclusion The diagnosis of SARS in Taiyuan is over-diagnosed. The positive rate of serum antibody gradually decreases with the passage of admission. Some confirmed cases are associated with ischemic necrosis of the femoral head after discharge.