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目的；在于研究ACNU治疗恶性脑肿瘤的疗效。方法：作者于1997年6月回顾性地分析、总结了1995～1996两年之间应用宁得朗（ACNU）治疗的脑胶质瘤20例和脑转移瘤3例的资料，并介绍了给药的方法、剂量和观察指标。结果：除1例多发脑转移瘤者未奏效，终因脑疝而死亡外，其余22例在随访时均还存活，其平均生存期限超越对照组，生存质量也优于对照组，手术的病例均未见复发。结论：初步分析揭示ACNU治疗恶性脑肿瘤有相当的效果。
The purpose is to study the efficacy of ACNU in the treatment of malignant brain tumors. Methods: The authors retrospectively analyzed and summarized the data of 20 cases of brain gliomas and 3 cases of brain metastases treated with ACNU within two years from 1995 to 1996, and summarized the data of Method, dosage and observation of medicine. Results: Except 1 case of multiple brain metastases who did not work and eventually died of herniation, the other 22 cases survived follow-up, the average survival time exceeded the control group, and the quality of life was better than that of the control group. The cases of operation No recurrence. CONCLUSIONS: The preliminary analysis revealed a significant effect of ACNU in the treatment of malignant brain tumors.