论文部分内容阅读
目的:分析泮托拉唑联合胃铋镁颗粒治疗消化性溃疡的效果。方法:选取怀集县妇幼保健院2016年1月至2017年2月收治的84例消化性溃疡患者,按用药方式分为观察组和参照组,在常规治疗的基础上,观察组采用泮托拉唑联合胃铋镁颗粒治疗,参照组采用泮托拉唑治疗,比较两组的治疗总有效率、溃疡愈合率、幽门螺旋杆菌(Hp)清除率、临床消化道症状改善情况以及临床不良反应等情况。结果:治疗后,观察组总有效率97.62%相较参照组78.57%更高;观察组溃疡愈合率88.10%相较参照组35.71%更高;观察组Hp清除率90.48%相较参照组66.67%更高,组间比较,差异具有统计学意义(P<0.05);两组临床不良反应发生率比较,差异无统计学意义(P>0.05)。结论:泮托拉唑联合胃铋镁颗粒对消化性溃疡患者有良好的治疗效果,安全性高。
Objective: To analyze the effect of Pantoprazole combined with Weizhi Magnesium Granules in treating peptic ulcer. Methods: Eighty-four patients with peptic ulcer admitted to Huaiji Maternal and Child Health Hospital from January 2016 to February 2017 were divided into observation group and reference group according to the way of treatment. On the basis of routine treatment, the observation group was treated with pantuo The combination of praziquantel and magnesium bismuth magnesium particles in treatment group and the treatment of pantoprazole in reference group were compared. The total effective rate of treatment, the healing rate of ulcer, the clearance rate of Helicobacter pylori (Hp), the clinical improvement of gastrointestinal symptoms and clinical adverse reactions And so on. Results: After treatment, the total effective rate in the observation group was 97.62%, which was higher than 78.57% in the reference group. The healing rate of ulcer in the observation group was 88.10% higher than that of the reference group (35.71%). The Hp clearance rate in the observation group was 90.48% (P <0.05). There was no significant difference in the incidence of clinical adverse reactions between the two groups (P> 0.05). Conclusion: Pantoprazole combined with bismuth magnesium particles have a good therapeutic effect on patients with peptic ulcer and high safety.