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目的观察低乳糖奶粉对婴幼儿轮状病毒肠炎并乳糖不耐受症的临床作用及恢复正常饮食的时机。方法将2013年9月—2015年7月,于本院儿科住院治疗的124例临床诊断为轮状病毒肠炎并乳糖不耐受症的患儿随机分成两组。对照组60例,给予补液纠酸、口服思密达、肠道益生菌等常规治疗,继续原喂养方式。治疗组64例,在常规治疗基础上,低乳糖奶粉喂养。观察两组治疗总有效率。治疗组有效的患儿在腹泻好转后分别给予低乳糖奶粉治疗1周及2周,然后逐渐恢复正常饮食,比较两组腹泻反弹情况。计数资料采用χ~2检验,P<0.05表示差异有统计学意义。结果治疗组总有效率高于对照组(95.3%、76.7%),对比差异有统计学意义(P<0.05)。低乳糖奶粉巩固喂养2周腹泻反弹率低于喂养1周(6.3%、20.7%),对比差异有统计学意义(P<0.05)。结论低乳糖奶粉佐治婴幼儿轮状病毒肠炎并乳糖不耐受症能提高常规治疗效果,缩短病程,且恢复正常饮食时间为喂养2周为宜。
Objective To observe the clinical effect of low lactose milk powder on infantile rotavirus enteritis and lactose intolerance and the timing of returning to normal diet. Methods From September 2013 to July 2015, 124 pediatric clinics diagnosed as rotavirus enteritis and lactose intolerance in our pediatric department were randomly divided into two groups. The control group of 60 patients given fluid correction acid, oral smecta, intestinal probiotics and other conventional treatment continue to feed. The treatment group of 64 cases, on the basis of routine treatment, low lactose milk powder feeding. The total effective rate of two groups was observed. Effective children in the treatment group were treated with low lactose milk powder for 1 week and 2 weeks after the diarrhea improved, and then gradually returned to the normal diet. The diarrhea rebound situation was compared between the two groups. Counting data using χ ~ 2 test, P <0.05 said the difference was statistically significant. Results The total effective rate of the treatment group was higher than that of the control group (95.3%, 76.7%), the difference was statistically significant (P <0.05). The rate of diarrhea rebound of low lactose milk fortified feeding for 2 weeks was lower than that of 1 week feeding (6.3%, 20.7%), the difference was statistically significant (P <0.05). Conclusion Low lactose milk powder for treating infantile rotavirus enteritis and lactose intolerance can improve the routine treatment effect, shorten the course of disease, and return to normal dietary time for feeding two weeks is appropriate.