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目的探讨通络调脂汤联合阿托伐他汀治疗稳定性冠心病合并高血脂症的疗效及对血液流变学指标的影响。方法将126例稳定性冠心病合并高血脂症患者按照随机数字表法分为实验组和对照组各63例。对照组采用阿托伐他汀治疗,实验组实施通络调脂汤联合阿托伐他汀治疗,观察2组治疗效果及治疗前后血液流变学情况。结果实验组治疗总有效率明显高于对照组(P<0.05);治疗后2组血脂水平、血液流变学指标、C反应蛋白均较治疗前明显降低,且实验组上述各项指标下降程度均较对照组更显著(P均<0.05)。结论通络调脂汤联合阿托伐他汀治疗稳定性冠心病合并高血脂症患者效果显著,对改善患者血脂水平及血液流变学情况也具有显著作用。
Objective To investigate the effect of Tongluozhili Decoction combined with atorvastatin in the treatment of stable coronary heart disease complicated with hyperlipidemia and its effect on hemorheology indexes. Methods 126 patients with stable coronary heart disease complicated with hyperlipidemia were randomly divided into experimental group and control group according to random number table method. The control group was treated with atorvastatin, and the experimental group was treated with Tongluozhitang combined with atorvastatin. The therapeutic effect and the hemorheology of the two groups were observed before and after treatment. Results The total effective rate of the experimental group was significantly higher than that of the control group (P <0.05). The levels of blood lipid, hemorheology and C-reactive protein in the two groups were significantly lower than those before treatment All were more significant than the control group (all P <0.05). Conclusion Tongluozhitang combined with atorvastatin in patients with stable coronary heart disease complicated with hyperlipidemia effect is significant, to improve the patient’s blood lipid levels and hemorheology also have a significant role.