一般认为 ,肠道损伤引起肠上皮下肌成纤维细胞的收缩、移行和增生反应是肠道创伤愈合过程中的重要步骤 ,但其产生及调控机制尚未得到充分研究。最近 ,加利福尼亚大学洛杉矶医学院生理医学系的学者研究了炎症介质内皮素 1对肠肌成纤维细胞的作用及其调节的信号转导通路。应用内 It is generally believed that intestinal injury causes intestinal contraction, migration and proliferation of intestinal submucosal fibroblasts is an important step in the process of intestinal wound healing, but its production and regulatory mechanisms have not yet been fully studied. Recently, a scholar at the Department of Physiology and Medicine at the University of California, Los Angeles, studied the role of the inflammatory mediator of endothelin-1 in intestinal fibroblasts and their regulatory signal transduction pathways. In-app