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目的:观察解毒疏络法对卵巢癌患者化疗后生活质量的影响。方法:设立单纯化疗组(对照组)30例,化疗加解毒疏络法组(治疗组)32例。以KPS评分、QLQ-C30生活质量调查问卷、FACT-O卵巢癌治疗功能评价系统、中医疗效评定标准、6m im行步距离及体重为指标进行临床疗效观察。结果:KPS评分治疗组32例,有效9例(28.1%)、稳定19例(59.4%)、下降4例(12.5%),对照组30例,有效4例(13.3%)、稳定13例(43.3%)、下降13例(43.3%),两组比较,差异有统计学意义(P<0.05);QLQ-C30生活质量调查问卷及FACT-O卵巢癌治疗功能评价系统评分,治疗组优于对照组(P<0.05);中医症状积分治疗组23.38±6.73较对照组29.32±5.31低(P<0.05);6m im步距离治疗组(318.4±31.2)m较对照组(243.5±29.4)m长(P<0.05);治疗组体重增加10例(31.3%)、稳定17例(53.1%)、减轻5例(15.7%),对照组体重增加3例(10.0%)、稳定11例(36.7%)、减轻16例(53.3%),两组比较,差异有统计学意义(P<0.05)。结论:解毒疏络法可一定程度改善化疗患者的生活质量。
Objective: To observe the effect of detoxification and detoxification on quality of life in patients with ovarian cancer after chemotherapy. Methods: Thirty patients in the simple chemotherapy group (control group) and 32 in the chemotherapy plus detoxification and sparing method group (treatment group) were enrolled. The clinical efficacy of KPS score, QLQ-C30 quality of life questionnaire, FACT-O ovarian cancer treatment function evaluation system, Chinese medicine curative effect evaluation standard, 6m im walking distance and body weight were taken as the indexes. Results: Thirty-two patients were treated in KPS group, 9 cases (28.1%) were effective, 19 cases (59.4%) were stabilized, 4 cases (12.5% (P <0.05); QLQ-C30 quality of life questionnaire and FACT-O ovarian cancer treatment evaluation system scores, the treatment group was better than the control group (43.3%), down 13 cases (43.3%), the difference between the two groups was statistically significant (P <0.05). The score of TCM symptom score group was 23.38 ± 6.73, which was lower than 29.32 ± 5.31 (P <0.05) in control symptom score group and 318.4 ± 31.2 m The body weight of the treatment group increased by 10.3% (31.3%), stabilized in 17 cases (53.1%), decreased in 5 cases (15.7%), increased in the control group by 3 cases (10.0% %), And 16 cases (53.3%) were alleviated. The difference between the two groups was statistically significant (P <0.05). Conclusion: detoxification and detoxification method can improve the quality of life of chemotherapy patients to some extent.