某些重金属对人类健康具有重要作用,但在工业化国家中它们是潜在的污染物。已证明有些重金属可以引起实验动物各种先天性畸形。由于在孕期接触镍能涉及胎儿毒性,故镍工业中女工数的增多令人关注。本文旨在研究着床前期给小鼠腹腔内注射氯化镍后胎鼠的发育。实验对象为2～4月龄雌性小鼠。雌雄鼠同笼交配后,检查阴栓以确定受孕时间。将NiCl_2· Some heavy metals have an important human health effect, but they are potential pollutants in industrialized countries. Some heavy metals have been shown to cause various congenital malformations in laboratory animals. As exposure to nickel during pregnancy involves fetal toxicity, an increase in the number of women in the nickel industry is of concern. This article aims to study the preimplantation mouse intraperitoneal injection of nickel chloride after fetal development. The subjects were 2 ~ 4 months old female mice. Male and female rats after mating with the cage, check the suppository to determine the time of conception. NiCl 2 ·