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目的观察腹腔镜联合促性腺激素释放激素激动剂治疗卵巢巧克力囊肿的临床疗效。方法选择在我院进行治疗的卵巢巧克力囊肿患者76例,按抽签顺序分为两组,各38例。对照组实施腹腔镜手术治疗,观察组在对照组基础上加用促性腺激素释放素激动剂治疗。将两组患者性激素水平、疗效、复发及受孕成功情况进行比较。结果治疗12个月后,观察组孕酮(P)、雌二醇(E2)、黄体生成素(LH)、血清卵泡刺激素(FSH)水平较对照组明显改善,差异有统计学意义(P<0.05);与对照组比较,观察组治疗总有效率明显提高,差异有统计学意义(P<0.05);观察组妊娠成功率较对照组明显提高,复发率明显降低,差异有统计学意义(P<0.05)。结论给予卵巢巧克力囊肿患者腹腔镜联合促性腺激素释放激素激动剂治疗效果确切,可改善患者性激素水平,提高术后妊娠成功率,降低复发率。
Objective To observe the clinical efficacy of laparoscopic combined with gonadotropin-releasing hormone agonist in the treatment of ovarian chocolate cyst. Methods 76 cases of ovarian chocolate cyst treated in our hospital were divided into two groups according to the order of lottery, 38 cases each. The control group was treated with laparoscopic surgery. The observation group was treated with gonadotropin-releasing hormone agonist on the basis of the control group. The two groups of patients with sex hormone levels, efficacy, recurrence and pregnancy success were compared. Results After 12 months of treatment, the levels of progesterone (P), estradiol (E2), luteinizing hormone (LH) and serum follicle stimulating hormone (FSH) in the observation group were significantly improved compared with the control group (P <0.05). Compared with the control group, the total effective rate of the observation group was significantly increased (P <0.05); the success rate of pregnancy in the observation group was significantly higher than that of the control group, the recurrence rate was significantly lower, the difference was statistically significant (P <0.05). Conclusions The laparoscopic combined with gonadotropin-releasing hormone agonist given to patients with ovarian chocolate cyst is effective in treating patients with sex hormones, improving the success rate of postoperative pregnancy and reducing the recurrence rate.