本文作者于1981年3～6月在海南黎族、苗族自治州4县1市调查21,446人,发现F地中海贫血患者60人,随机选择11个家族作进一步调查,结果在60名家系成员中又发现杂合子F地中海贫血33例并进行了有关遗传、生化、临床和实验研究,现综合报告如下。材料和方法一、调查对象:海南黎族、苗族自治州琼中、保亭、乐东、崖县及通什等4县1市的大、中、小学生共21,446人,对F地中海贫血11个家族33例阳性患者进行有关调查研究。二、调查研究项目:包括临床和家族病史的询问、体检、血常规、红细胞形态观察,红 The authors investigated 21,446 people from 4 counties and 1 city in Hainan’s Li and Miao autonomous prefectures from March to June 1981 and found 60 F-thalassemia patients were randomly selected from 11 families for further investigation. As a result, among 60 family members, they were also found to be miscellaneous Zygophobia 33 cases of thalassemia and carried out on the genetic, biochemical, clinical and experimental studies, the comprehensive report is as follows. MATERIALS AND METHODS A. Surveyed subjects: 21,446 primary, secondary and primary school students in four counties and one city of Qiongzhong, Baoting, Ledong, Yaxian and Tongshi of Hainan Li and Miao Autonomous Prefecture, investigated 11 families of F thalassemia Cases of positive patients for the investigation. Second, the investigation and research projects: including clinical and family history of inquiry, physical examination, blood, erythrocyte morphology, red