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目的 探讨心肌梗死前 2 4小时内的缺血预适应 (IP)现象对急性心肌梗死 (AMI)范围及近期预后的影响。方法 对 1 44例急性Q波心肌梗死的病人进行回顾性分析。根据心肌梗死前有无典型的心绞痛发作分为两组 :A组 (IP) 45例 ,发病前 2 4小时内有典型的心绞痛发作 ;B组 99例 ,发病前 2 4小时内无典型的心绞痛发作。结果 A组多为前壁梗死 ,心肌梗死面积、CK峰值、严重心衰及严重室性心律失常的发生率、住院病死率均显著低于B组 (P <0 .0 5或P <0 .0 1 )。结论 AMI前 2 4小时内的IP现象可以缩小心肌梗死面积 ,改善心肌梗死的近期预后 ,降低住院病死率
Objective To investigate the effect of ischemic preconditioning (IP) within 24 hours before myocardial infarction on the range and immediate prognosis of acute myocardial infarction (AMI). Methods One hundred and forty-four patients with acute Q wave myocardial infarction were retrospectively analyzed. According to the presence of typical myocardial infarction before and after the onset of angina pectoris is divided into two groups: A group (IP) 45 cases, 24 hours before the onset of typical angina pectoris; 99 cases of group B, within 24 hours before onset without typical angina pectoris attack. Results In group A, the incidence of anterior wall infarction, myocardial infarct size, CK peak, severe heart failure and severe ventricular arrhythmia, and hospital mortality were significantly lower than those in group B (P <0.05 or P <0.05). 0 1). Conclusion The IP phenomenon within 24 hours before AMI can reduce the infarct size, improve the short-term prognosis of myocardial infarction and reduce the in-hospital mortality