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目的 观察静脉应用地尔硫 艹卓 控制阵发性心房颤动时快速心室反应的效果。方法 将 5 9例阵发性心房颤动伴快速心室率者随机分为地尔硫 艹卓 治疗组 30例和毛花甙丙组 2 9例 ,观察用药后的心室率和血压变化。结果 地尔硫艹卓 组用药后心室率从 14 1次± 18次 / min,降至 82次± 10次 / min,毛花甙丙组用药后心室率从 14 2次± 15次 / min,降至88次± 11次 / min,两组最大效应时间前者为 7.0 min± 2 .5 min,后者为 10 5 min± 2 9min,P<0 .0 1,地尔硫 艹卓 组有效率为93.3% ,毛花苷丙组为 72 .4 % ,P<0 .0 5。地尔硫 艹卓 组有 2例出现一过性无症状性低血压 ,无需处理。结论 静脉应用地尔硫 艹卓 能快速、有效和安全地控制阵发性心房颤动时快速心室反应
Objective To observe the effect of intravenous diltiazem on rapid ventricular response in patients with paroxysmal atrial fibrillation. Methods Fifty-nine patients with paroxysmal atrial fibrillation and rapid ventricular rate were randomly divided into 30 cases of diltiazem group and 29 cases of curculigin group. The changes of ventricular rate and blood pressure were observed. Results After oral administration of diltiazem, the ventricular rate decreased from 14 1 ± 18 / min to 82 ± 10 / min, and the percentage of ventricular from 14 2 ± 15 / min in the curcumin group C, To 88 times ± 11 times / min, the maximum effective time of the two groups was 7.0 min ± 2.5 min, the latter was 105 min ± 29 min, P <0.01, the effective rate of diltiazem group Was 93.3%, and the glycoside C group was 72.4%, P <0.05. In the diltiazem group, 2 patients had transient asymptomatic hypotension without treatment. Conclusion Intravenous Diltiazem can rapidly, effectively and safely control paroxysmal atrial fibrillation during rapid ventricular response