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目的:探讨血浆置换(PE)治疗急性重症有机磷农药中毒(ASOPP)的疗效。方法:将2011年1月-2014年5月收治的ASOPP患者62例随机分为对照组和研究组各31例,分别常规疗法和联合应用PE治疗,比较两组的临床疗效。结果:与对照组相比,研究组阿托品化、显著效果的时间和住院时间均明显缩短,中间综合征、反跳例数、死亡率均明显减少,治愈率明显增高,P均<0.05。结论:在常规治疗的基础上联合PE治疗ASOPP的抢救成功率高,死亡率低,并发症少。
Objective: To investigate the efficacy of plasma exchange (PE) in the treatment of acute severe organophosphorus pesticide poisoning (ASOPP). Methods: Sixty-two ASOPP patients admitted to our hospital from January 2011 to May 2014 were randomly divided into control group and study group (n = 31). Conventional and combined PE were used respectively to compare the clinical efficacy of the two groups. Results: Compared with the control group, the study group atropine, significant effect of time and hospitalization were significantly shorter, intermediate syndrome, anti-jumping cases, mortality were significantly reduced, the cure rate was significantly higher, P <0.05. Conclusion: The combination of PE and conventional PE has a high success rate of rescue, low mortality and few complications.