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本文测定了105例正常人和32例冠心病患者血浆脂酰氢过氧化物(AHP)、总脂(TL)和总胆固醇(TC)含量,发现冠心病患者血浆AHP水平显著高于正常人(P<0.01),超过正常上限者占71.9％。血浆TC含量的差别亦有显著性(P<0.05),但超过正常上限者占43.8％。血浆TL值无明显差异(P>0.05),而且超过正常上限者仅占12.5％。结果表明,血浆AHP水平较TC和TL的变化更明显,临床上常规测定血浆AHP水平,可作为冠心病辅助诊断和判断防治效果的一种生化指标。
In this study, the serum levels of lipid acyl hydroperoxide (AHP), total lipids (TL) and total cholesterol (TC) in 105 normal subjects and 32 patients with coronary heart disease were measured. The plasma levels of AHP in patients with coronary heart disease were significantly higher than those in normal subjects P <0.01), more than the upper limit of normal accounted for 71.9%. There was also a significant difference in plasma TC levels (P <0.05), but 43.8% exceeded normal upper limits. Plasma TL value was no significant difference (P> 0.05), and more than the upper limit of normal accounted for only 12.5%. The results showed that plasma AHP levels more obvious changes than TC and TL, the clinical routine determination of plasma levels of AHP can be used as a secondary diagnosis of coronary heart disease and determine the effect of a biochemical indicators.