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目的:为了深入分析肾内科住院病患产生真菌感染的表现特点以及各种危险因素,以便制定相应策略。方法:选取2012年5月到2013年5月在我院肾内科进行住院治疗的病患418例,其中有13例病患在住院期间产生深度真菌感染,将其作为研究组,另外将13例住院期间没有产生真菌感染的病患作为对照组,回顾分析两组病患的临床资料以及引发真菌感染的危险因素。结果:经对比发现,研究组中病患患有糖尿病的比重,抗菌药物使用情况、糖皮质激素使用量、透析例数等都比对照组高,P<0.05,具有统计学差异意义;研究组中病患的血清白蛋白与血红蛋白都比对照组低,P<0.05,具有统计学差异意义。结论:在我院肾内科进行住院治疗的病患,易产生深度真菌感染,特别是呼吸道感染,诱发深度真菌感染的原因主要有:抗菌药物使用较频繁、年龄大、营养不良、糖皮质激素、透析、糖尿病等。
Objective: In order to analyze in-depth analysis of in-hospital nephrotic inpatients with fungal infection characteristics and various risk factors in order to develop the appropriate strategy. METHODS: A total of 418 hospitalized patients with nephrology in our hospital from May 2012 to May 2013 were selected. Among them, 13 patients had deep fungal infection during hospitalization and were included in the study group. In addition, 13 patients During hospitalization, no patients with fungal infection were taken as control group. The clinical data of two groups of patients and the risk factors causing fungal infection were retrospectively analyzed. Results: Compared with the control group, the proportion of patients with diabetes mellitus, the use of antimicrobial agents, the amount of glucocorticoid and the number of dialysis patients in the study group were significantly higher than those in the control group (P <0.05). The study group In patients with serum albumin and hemoglobin than the control group, P <0.05, with statistical significance. CONCLUSIONS: Patients hospitalized with nephrology in our hospital are prone to have deep fungal infections, especially respiratory infections. The main causes of deep fungal infections are: frequent use of antimicrobial agents, age, malnutrition, glucocorticoids, Dialysis, diabetes and so on.