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目的:探讨生物羊膜(AMT)与丝裂霉素(MMC)在难治性青光眼中的治疗效果及护理方法。方法:将47例(73眼)难治性青光眼患者随机分为AMT组22例(33眼)与MMC组25例(40眼),并给予精心观察与护理,比较两组手术疗效。结果:两组术后6、12个月眼压比较差异有统计学意义(P<0.05),AMT组在术后1个月内视力不变或提高、术后视力下降发面优于MMC组(P<0.05)。结论:应用生物羊膜可有效防止术后滤过泡瘢痕组织形成,是治疗难治性青光眼安全、经济、有效的新方法,通过加强术前心理护理及术后并发症观察与护理保证了手术疗效。
Objective: To investigate the therapeutic effects and nursing methods of biological amniotic membrane (AMT) and mitomycin (MMC) in refractory glaucoma. Methods: Forty-seven patients (73 eyes) with refractory glaucoma were randomly divided into AMT group (22 eyes) and MMC group (25 eyes) (25 eyes). Meticulous observation and nursing were given. The curative effect was compared between the two groups. Results: There was significant difference in IOP between the two groups (P <0.05) at 6 and 12 months after operation. The visual acuity was unchanged or increased within one month after operation in AMT group, (P <0.05). Conclusion: The application of biological amniotic membrane can effectively prevent the formation of scar tissue after filtering bleb, which is a safe, economical and effective method for the treatment of refractory glaucoma. Surgical efficacy can be guaranteed by strengthening preoperative psychological nursing and postoperative complications observation and nursing .