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目的:研究儿童肺炎支原体(MP)感染肺外并发症的构成与致病菌分布,并探讨相应的预防对策。方法:收集2015年5月—2016年5月间收治的MP感染患者634例,分析其中伴有肺外并发症患儿268例的临床特点、并发症构成、伴有患儿痰标本检测中病原菌的构成及实验室指标,探讨相应的预防对策。结果:调查发现不同年龄组别患儿并发症的发生率经组间比较其差异有统计学意义(χ~2=8.09,P<0.05);MP感染并发症患儿,其并发症主要累及系统及构成比也有所不同;MP感染伴有肺外并发症患儿的痰标本中,检出的病原菌数量及检出构成比也有较大区别;在MP感染伴有并发症的患儿与MP患儿血常规的比较中,白细胞计数(t=9.66,P<0.05)、血沉(t=43.90,P<0.05)、红细胞计数(t=13.64,P<0.05)、血小板计数(t=9.18,P<0.05)、血红蛋白计数(t=22.55,P<0.05);MP感染伴有并发症患儿与MP患儿各免疫功能指标影响的比较中,其中淋巴细胞绝对值(t=4.79,P<0.05)、中性粒细胞绝对值(t=2.40,P<0.05)、嗜碱性粒细胞绝对值(t=8.65,P<0.05)、痰液革兰染色单核细胞绝对值(t=20.27,P<0.05);血清特异性IGM抗体水平(t=4.49,P<0.05)。结论:通过对儿童肺炎支原体感染肺外并发症的构成分析,结果累及各系统并发症的构成比经组间比较其差异有统计学意义,采用抗生素预防治疗,效果较为理想。
Objective: To study the distribution and pathogens distribution of extrapulmonary complication in children with Mycoplasma pneumoniae (MP) infection and to explore the corresponding preventive measures. Methods: 634 cases of MP infection were collected from May 2015 to May 2016. The clinical features, complications and complications of 268 patients with extrapulmonary complication were analyzed. Pathogens Composition and laboratory indicators to explore the appropriate preventive measures. Results: The incidence of complications in children of different age groups was statistically significant (χ ~ 2 = 8.09, P <0.05). The complication in children with MP infection mainly involved the system And composition ratio is also different; MP infection with pulmonary complications in children with sputum specimens, the number of pathogens detected and the detection of constituent ratio are also significantly different; MP infection in children with complications and MP The blood routine test showed that the white blood cell count (t = 9.66, P <0.05), erythrocyte sedimentation rate (t = 43.90, P < (T = 4.79, P <0.05), and the hemoglobin count (t = 22.55, P <0.05). Among the MP patients with MP and MP, , Absolute value of neutrophil (t = 2.40, P <0.05), absolute value of basophil (t = 8.65, P <0.05) P <0.05). Serum specific IGM antibody level (t = 4.49, P <0.05). Conclusion: Through the analysis of the complication of extrapulmonary complication of Mycoplasma pneumoniae infection in children, the results involved in the composition of each system comparisons were statistically significant compared with those of the inter-group. Antibiotic prophylaxis was the best.